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GTA VI launches on

Three Fooliganz members posing with rifles in The Last Dose, the conclusion of Los Santos Drug Wars in GTA Online.

GTA Online: The Last Dose is out — missions and how to get the Ocelot Virtue

The Last Dose is live in GTA Online: the five missions of the Los Santos Drug Wars finale, Dr. Friedlander and how to claim the Ocelot Virtue for free.

This article is from March 16, 2023. Some details may have changed since then.

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The Last Dose arrived in GTA Online on March 16, 2023, as Rockstar had announced a week earlier. It’s the finale of Los Santos Drug Wars: five missions in which Dax, Luchadora and the rest of the Fooliganz uncover a pharmaceutical conspiracy while dealing with some very strong psychedelics.

How to start

Wait for Dax’s call or head straight to The Freakshop. If you haven’t played part one yet, start The First Dose by visiting Nervous Ron at Liquor Ace in Blaine County: six missions that give you the HQ, the mobile Acid Lab and the story’s groundwork. We cover it in our Los Santos Drug Wars article.

The five missions

Mission

What you do

This is an Intervention

The Fooliganz’ annual get-together goes sideways; bring armour and automatic weapons

Unusual Suspects

Lean on The Lost and their hippie allies to find out who took Labrat — without killing the leaders who can talk

FriedMind

Raid FriedMind Pharmaceuticals HQ, gather clues and rescue the missing crew; stealth helps

Checking In

Hit a rehab centre trialling Labrat’s stolen recipe and keep Dax and Luchadora alive

BDKD

Wipe out the competition’s remaining stock and cover Dax while he grabs every last bit of product

Two Fooliganz members talking in a graffiti-covered room during the Unusual Suspects mission.
A shotgun-toting Fooligan moving down a white corridor past two men in lab coats in the FriedMind mission.
Luchadora holding a rifle surrounded by alien figures in a psychedelic scene during Checking In.
A Fooligan peering out of a private jet window in the BDKD mission.

The villain: Dr. Friedlander

Dr. Isiah Friedlander, Michael De Santa’s therapist in GTA V, has launched FriedMind Pharmaceuticals to get into the drug business. His brand sells, but his product can’t match what’s on the street, so he turns to kidnapping, dosing and hired mercs to get an edge. It’s one of GTA Online’s best nods to the GTA V story.

The Ocelot Virtue, free when you finish

The new Ocelot Virtue is an all-electric hypercar. Complete every Last Dose mission and you’ll get Friedlander’s personal Virtue in FriedMind livery for free. It takes Imani Tech upgrades at the Agency Vehicle Workshop.

Silver Ocelot Virtue with an iridescent finish on a white background.
Ocelot Virtue in FriedMind Pharmaceuticals livery on a wet Los Santos street.

Is it worth it?

Yes, especially if you own the Acid Lab: it’s one of the most profitable solo-friendly businesses, and the full Los Santos Drug Wars story is among GTA Online’s wildest. Besides the Virtue, the update added new cardigans and wide-leg jeans to clothing stores.